October 2024
Welcome to Bhumika and Devanshika doing their BSc internships!
Our work showing that two small molecule inhibitors, Isoginkgetin and Madrasin, are poor inhibitors of pre-mRNA splicing has been published in PLOS One! [ARTICLE]
July 2024
Our latest preprint on characterising how the activity of the splicing factor SF3B1 regulates via multiple pathways the recruitment of the key transcriptional complex P-TEFb is out! [PREPRINT]
April 2024
Our collaborative project with Prof. Ian Eperon (University of Leicester, UK) and Dr Sylvain Egloff (CBI, France) on determining the role of SMN/7SK complex in the regulation of gene expression has been funded by cureSMA! https://www.curesma.org/tellier-grant-announcement-2024/
February 2024
Our latest collaborative preprint with the research groups of Dr Takayuki Nojima, Prof. Ali Shilatifard, and Dr Yasu Daigaku on a novel function of NELF in transcription elongation and termination is out! [PREPRINT]
January 2024
Welcome to Eray and Yalin doing a MSc and a BSc internship, respectively!
Our collaboration on investigating the role in the nucleus of iRhom2 cleaved N-terminus has been published in Molecular Cell! [ARTICLE]
October 2023
Welcome to Yagiz and Thomas, the first two PhD students of the lab, and to Nulenie, a BSc student doing her third year project!
September 2023
Our collaboration on characterising the role of APOBEC3B in the resolution of R-loops and its consequences and transcription-associated mutagenesis is out in Nature Genetics! [ARTICLE]
June 2023
Our latest research on the role of RNA processing efficiency in the production of mature mRNA is now published in NAR Genomics and Bioinformatics! [ARTICLE]
Our collaboration with Prof. Alexandra Moreira (ICBAS, University of Porto) on the influence of colorectal cancer and pro-inflammatory polarization on poly(A) sites usage of primary human macrophages has been published in Frontiers in Immunology. [ARTICLE]
February 2023
Our collaboration with Prof. Xin Lu (Ludwig Institute, University of Oxford) on the functions of the p53-inhibitor iASPP in the regulation of immunological tolerance has been published in Cell Death & Disease! [ARTICLE]
January 2023
Our work on the effects of different splicing inhibitors on transcription has been submitted. [PREPRINT]