Tellier Lab @ University of Leicester
Protein phosphorylation and regulation of gene expression
The Tellier lab is interested in understanding how protein phosphorylation contribute to the regulation of transcription and co-transcriptional processes, including pre-mRNA splicing and mRNA cleavage and polyadenylation.
To achieve this we use cutting-edge molecular, genomic, biochemical, and cellular approaches in human cell lines.
Ultimately, our motivation is to understand how protein phosphorylation regulate the production of mature mRNAs in normal cell biology to develop therapeutic approaches to counteract its perturbation in cancer and other human diseases.
We have PhD projects available in the lab! Feel free to contact Dr Tellier for more information.
BBSRC MIBTP programme (open to UK & International students): Unravelling age-related gene expression dysregulation through system biology and mathematical modelling (Collaboration with Dr Massimo Cavallaro, University of Leicester, deadline: 16th January 2025)
MRC AIM DTP programme (open to UK & International students): Understanding the role of cancer-associated SF3B1 mutation in microRNA biogenesis (Collaboration with Dr Catherine Jopling, University of Nottingham, deadline: 10th January 2025)
Chinese Scholarship Council partnership PhD (Chinese citizen only): Contact Dr Tellier if you want to develop a project in the regulation of gene expression.
Self-funded PhD: Transcriptional kinases in cancer and developmental disorders